A Disease of Massive Proportions.

There are presently approximately 30 million diabetics in the U.S. and about 400 million worldwide, some 90+% of which are Type 2 who develop insulin resistance over time, as opposed to Type 1 diabetics whose bodies do not produce insulin at all.  This is, by population, the most common disease in the world.

Various estimates put the growth rate of the disease at between 10%-15% annually.  What is clear is that many experts have vastly underestimated the scope of this pandemic.  It seems to be accelerating.  For example, according to a 2001 study in the American Diabetes Association magazine, Diabetes Care, “The number of Americans with diagnosed diabetes is projected to increase 165%, from 11 million in 2000 to 29 million in 2050.”  America passed the projection for 2050 by 2015, 35 five years SOONER than expected.  This same phenomenon has occurred in other parts of the world.

All told diabetes affects over 1 billion people around the globe.  According to Alfred Mann, a pioneer in the field, "diabetes is not the greatest healthcare challenge facing the world.  It is the greatest challenge facing the world".

Poor Control.

Diabetes is a chronic, incurable condition that worsens with time.  Without medication it is fatal.

The recognized, standard measurement of the control of one’s diabetes is something called HbA1c.  The lower HbA1c, the better.  Normal, non-diabetic patients have levels below 5.7.  At a level above 6 a person is considered diabetic.  Presently, the very best managed diabetic patients have levels at about 6.5.  Most diabetics are above 7.  Also, HbA1c levels get worse with time.  It’s a little like vision in the sense that once a person begins correcting vision, every couple years that person needs a stronger correction.  A diabetic with an HbA1c of 6.5 will, in time, have much higher numbers.

To put these HbA1c numbers in perspective, one needs to understand how they correlate to blood glucose levels.  See Table 1 below.  Generally an HbA1c reading of 5 corresponds to an average blood glucose level of about 100.  You can see the corresponding blood glucose values as HbA1c rises.   Importantly, blood glucose levels are what drive the problems that bedevil diabetics.  Elevated glucose levels maintained for a number of years will result in severe problems.  Microvascular damage begins to occur at blood glucose levels of 140 and above.  Long term microvascular damage is what causes the problems associated with diabetes like heart disease, stroke, blindness, kidney failure, amputations, peripheral neuropathy etc.  All worsen as blood glucose rises.  A blood glucose level of 140 corresponds to an HbA1c of approximately 6.5.  Yet, as previously stated, most patients are well above this level.

More troubling, the American Diabetes Association generally guides physicians to manage their diabetic patients to an HbA1c between 6.5 and 7.  Why would the experts in the field recommend blood glucose levels in a range that virtually guarantees long term damage? The answer is... hypoglycemia.

Table 1

HbA1c (%) eAG (mg/dL) eAG (mmol/l)
5 97 5.4
6 126 7.0
7 154 8.6
8 183 10.2
9 212 11.8
10 240 13.4
11 269 14.9
12 298 16.5


Hypoglycemia is the condition of low blood glucose.  At the extremes, hypoglycemia can cause brain damage, coma or death.

Further, hypoglycemia often occurs at night when a diabetic is asleep so the onset can be unnoticed until it is too late.  Blood glucose levels fluctuate wildly throughout the day.  To keep the blood glucose level from going too low, the experts recommend keeping the average level at a higher than optimal point.  In other words, to reduce the possibility of death from hypoglycemia in the short term, the experts recommend average glucose levels that are likely to lead to death in the long term.

The average type 1 diabetic dies about 10 years sooner than normal, and the average type 2 dies 6 -10 years earlier than normal.  Higher HbA1c means a shorter life.

The Goldilocks Problem – Too High, Too Low.

So, as you see from the discussion surrounding Table 1 above, blood glucose levels that are too high can lead to very serious long-term complications, but glucose levels that are too low can result in very severe short-term complications.  And, compounding this problem is the fact that the patient cannot see his/her blood glucose levels.  It’s not until blood glucose levels get extreme in either direction that some patients can begin to notice.  By this point, however, it could be too late.  This is the key to understanding the difficulty in treating this disease.

The Goal of Vdex.

We at Vdex believe with the latest therapies and technological innovations, our patients can SAFELY maintain average HbA1c levels significantly below 6.5 and even 6.0.  A significant number of patients using Vdex protocols actually have HbA1c levels BELOW 6.0, all with NO INCREASE IN HYPOGLYCEMIA.


A Revolution has come to diabetes.

Note the use of the past tense.  It’s not something that’s going to happen.  It’s here now.

Developed by a physicist and not a physician, it’s Afrezza.

Like all revolutions, this one has toppled an established order.  Historically, blood sugar control was a battle between being too high or too low, hyperglycemia or hypoglycemia.  Historically, as one lowered HbA1c, one increased the hypoglycemic risk.  Historically, good control meant pain: injections and finger sticks.

All that’s been swept aside.  It’s history.  For too long, diabetes has been a curse for patients and a burden for their loved ones.

It stops NOW.  No more.

Through the use of Afrezza, Vdex has one simple aim: to ENABLE DIABETICS TO LIVE A NORMAL OR NEARLY NORMAL LIFE.

A disease unlike most other medical conditions, diabetes is a chronic condition with devastating long-term consequences.
It requires hour-by-hour attention to avoid equally devastating short-term consequences.  Patients need regular care and monitoring for life.

Through our "Real Time Diabetes Management" model, diabetics have far better control of blood glucose levels and reduced hypoglycemia as compared to the current, best therapies available today.

Revolutions are usually borne of the people.  People with diabetes died 10 – 15 years sooner than non-diabetics.  People with diabetes suffered with monstrous complications.  People with diabetes were notoriously non-compliant.  People are now free to live a new, fuller life with diabetes, one where they’re in control.

Revolutions face long odds of success and only seem obvious in retrospect.  But you don't have to wait for the revolution, you can join it now.

We have distilled our belief for the future of this disease to the following:

Afrezza first, Afrezza instead, Afrezza always.


For more information download the Vdex white paper on Afrezza here.

I've participated in the design of the Vdex treatment protocols.  In fact I use them myself in the management of my own diabetes.  I've seen the results.  I live with the results everyday. I do not micromanage my diabetes with carb counting. Before these treatment protocols my A1c was 7.5.  Now it's a lifetime best 6.2. Im a very competitive person and always tried to lower my a1c every time i visited my doctor. Now instead of dreading doctor visits, I'm excited to see the progress I've made. This works.  Every diabetic needs to learn about this."

Eric F. Type 1 since 10/22/1993


Real Time Diabetes Control hasn't been possible until the advent of VDEX. They're changing the way diabetes is managed by offering custom solutions, based on patient needs. The people behind VDEX weren't content with the current level of diabetes care, seeing that massive room for improvement was possible. I believe that given the opportunity they have the capabilities to improve the quality of life for everyone who is lucky enough to be involved.

Jerry T.


More so than any other disease, Diabetes should be managed the way VDEX does it. It's a peculiar disease and as an orthopedic surgeon, I saw the ravages of it personally. It requires more oversight than most doctors have time for. When someone has diabetes aged 25 they don't think about what life will be like aged 65. The long-term complications don't get attention at the early stages of the disease but diabetic neuropathy is very troublesome because it's irreversible. It's a terrible terrible disease. VDEX is the answer.

Paul M. Orthopedic Surgeon.

Louis & Steve R. Napa, CA Sandy G. Sylmar, CA
Lindsay B. Oxnard, CA Atticus T. Los Angeles, CA

To submit your own patient testimonial, click here. Please note that each video will go through an approval process before being added to the site.

In Memoriam

Alfred E. Mann, 1925 - 2016

Vdex Diabetes is dedicated to the memory of Alfred Mann who was responsible for the betterment of so many lives both diabetic and otherwise.  Al lived his life in a manner that serves as a model to us all.  His focus, both personally and professionally, was on solving problems for others.  We at Vdex strive humbly to carry on his legacy in the field of diabetes.  Whatever success we enjoy will forever rest upon the foundation created by Al Mann.

Developing a future together.

Thank you for all of your continued interest in Vdex Diabetes.

We are pleased to announce the opening of our first Diabetes Treatment Center. We look forward to serving you.

Questions & Comments

If you have any questions or would just like more information regarding our services, please fill out the form below and one of our representatives will get back to you. Alternatively you can visit our Facebook, Twitter  or Instagram pages for further information.

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Information & Consultation

Please fill out the form below to request more information or schedule an appointment at our Canoga Park, CA location. More locations will be activated as they become available.

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Interested in helping people beat Diabetes?

Open your own VDex location...

The Vdex licensing program is NOT a franchise program. Vdex acts as a consultant to assist you in establishing your own practice helping people with diabetes beat this disease.

We provide you with a formula for establishing your business/practice along with medical expertise and research findings for your consideration and use. We also provide on-going consultation and marketing support. You provide the entrepreneurial drive.

Any person can have a Vdex Diabetes practice. You don’t need to be a physician. The important point for non-physicians is that a licensed physician (or in some states, non-physician medical provider) must provide, or oversee the provision of, medical services. (Each state has its own medical regulations. We recommend legal guidance for anyone considering participating.)

Setting up a Vdex Diabetes practice is NOT capital intensive, as compared to similar, franchise-type operations. Based on the experiences we had opening our own locations, we can guide you away from the potential pitfalls that come with any entrepreneurial venture. The most important quality is the drive to help people.

The first step is to complete and submit the Vdex Participation Form below.  Following that, a Vdex Representative will contact you. 

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